Big Ten football picks and spreads for Week 5 of the 2015 college football season. This week’s slate has seven games, including the No. 1 Ohio State Buckeyes traveling to Bloomington to take on the Indiana Hoosiers in their conference opener. Will the Buckeyes extend their winning streak to 18 games, or will the Hoosiers pull off the upset? Scroll down for the Big Ten picks.

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Week 5 Big Ten Football Picks And Spreads

Army at Penn State

Date: Saturday, Oct. 3

Kickoff: 12:00 p.m. ET

Venue: Beaver Stadium

The Nittany Lions defensive front seven will try to stop the ground attack of the Black Knights, which has been struggling a bit so far this season. Penn State quarterback Christian Hackenberg has been solid of late, throwing for 328 yards and three touchdowns last week. The Nittany Lions make easy work of the Black Knights. 

Pick: Penn State
Spread: Penn State -26

For final score prediction, check out our Penn State vs. Army game preview.

No. 22 Michigan at Maryland

Date: Saturday, Oct. 3

Kickoff: 12:00 p.m. ET

Venue: Byrd Stadium

Michigan has found its footing in coach Jim Harbaugh’s first season, and the Wolverines are looking to open Big Ten play with a victory. The Terrapins have been struggling, getting blown out by West Virginia and losing to Bowling Green. A Big Ten victory would help Maryland get back on the right path, but that won’t come this week.

Pick: Michigan
Spread: Michigan -15.5

For final score prediction, check out our Michigan vs. Maryland game preview.

Iowa at No. 19 Wisconsin

Date: Saturday, Oct. 3

Kickoff: 12:00 p.m. ET

Venue: Camp Randall Stadium

Ever since the opening game to Alabama, Wisconsin has been rolling, although against inferior competition. Iowa running back Jordan Canzeri has been terrific so far this season, but will face a tough defense in the Badgers, which will be the difference maker. 

Pick: Wisconsin
Spread: Wisconsin -7

For final score prediction, check out our Wisconsin vs. Iowa game preview.

Minnesota at No. 16 Northwestern

Date: Saturday, Oct. 3

Kickoff: 12:00 p.m. ET

Venue: Ryan Field

Northwestern has been the surprise team of the season so far, starting 4-0 with wins over Stanford and Duke. Neither the Wildcats nor Golden Gophers have much of a passing game, so whoever can control the ball on the ground will walk out a winner. Minnesota grinds this one out on the road. 

Pick: Minnesota
Spread: Northwestern -4

For final score prediction, check out our Northwestern vs. Minnesota game preview.

Purdue at No. 2 Michigan State

Date: Saturday, Oct. 3

Kickoff: 12:00 p.m. ET

Venue: Spartan Stadium

The Spartans have been chugging along, starting the season 4-0 with a big win against Oregon. Purdue, on the other hand, has been struggling. The Boilermakers will need a big game from quarterback David Blough to stay in this game. Sparty pulls away for an easy victory. 

Pick: Michigan State
Spread: Michigan State -22

For final score prediction, check out our Michigan State vs. Purdue game preview.

No. 1 Ohio State at Indiana

Date: Saturday, Oct. 3

Kickoff: 3:30 p.m. ET

Venue: Memorial Stadium

The Buckeyes haven’t been as dominant as expected, but are still undefeated. Coach Urban Meyer has used both J.T. Barrett and Cardale Jones under center, while running back Ezekiel Elliott has been terrific. Quarterback Nate Sudfield leads a balanced Hoosiers offense that will have to keep up with the Buckeyes on the scoreboard. Ohio State wins by four scores. 

Pick: Ohio State
Spread: Ohio State -21

For final score prediction, check out our Ohio State vs. Indiana game preview.

Nebraska at Illinois

Date: Saturday, Oct. 3

Kickoff: 4:02 p.m. ET

Venue: Memorial Stadium

The Cornhuskers are led by quarterback Tommy Armstrong Jr., who has been solid so far this season. He will face a tough Illini defense that has a stout front seven and is excellent on third downs. Armstrong and the Huskers find a way to get it done on the road. 

Pick: Nebraska
Spread: Nebraska -6.5

For final score prediction, check out our Nebraska vs. Illinois game preview.