The Big 12 is back in action for Week 2 of the college football season, with the Kansas State Wildcats kicking things off at 12:00 p.m. ET on Saturday. The Wildcats will hit the road to play the UTSA Roadrunners.

In afternoon action, No. 3 TCU hosts Stephen F. Austin at 3:30 p.m. ET and Iowa State hosts in-state rival Iowa at 4:45 p.m. ET.

In the marquee game of the week, No. 19 Oklahoma visits Rocky Top to take on No. 23 Tennessee in a 6:00 p.m. ET kickoff. Bob Stoops and the Sooners are hoping to make it two straight wins over the Vols. 

Texas and Rice will cap things off on Saturday night at 8:00 p.m. ET. Charlie Strong and the Longhorns are looking to rebound from a blowout to Notre Dame to open the season.

The rest of the Week 2 Big 12 football schedule is listed below, as well as picks and previews.

Week 2 Big 12 Football Schedule

Saturday, September 12

Note: All times Eastern.

12:00 PM Kansas State at UTSA, FS1

3:00 PM Liberty at West Virginia, ROOT Sports

3:00 PM UTEP at Texas Tech, FSN

3:30 PM Stephen F. Austin at No. 3 TCU, FS1

4:45 PM Iowa at Iowa State, FOX

6:00 PM No. 19 Oklahoma at No. 23 Tennessee, ESPN

7:00 PM Memphis at Kansas, Jayhawk TV

7:30 PM Central Arkansas at Oklahoma State, FSN

7:30 PM Lamar at No. 4 Baylor, FSN

8:00 PM Rice at Texas, Longhorn Network

Week 2 Big 12 Football Picks & Predictions

• Kansas State at UTSA
• Liberty at West Virginia
• UTEP at Texas Tech
• Stephen F. Austin at No. 3 TCU
• Iowa at Iowa State
• No. 19 Oklahoma at No. 23 Tennessee
• Memphis at Kansas
• Central Arkansas at Oklahoma State
• Lamar at No. 4 Baylor
• Rice at Texas

WATCH: Inside The College Football Playoff Rankings, Week 1