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Big 12 football predictions and schedule for Week 6 of the 2016 season. In the marque game, Texas will look for its second consecutive win against Oklahoma in the Red River Rivalry.

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With conference leaders Baylor and West Virginia on a bye, Week 6 of Big 12 action features four conference matchups.

Starting the action is the week’s headliner, the Red River Rivalry. Charlie Strong is likely coaching for his job when his Texas Longhorns meet the Oklahoma Sooners at the Cotton Bowl. Meanwhile, Oklahoma is hoping to minimize its losses on the year, keep it at two for the season, and run the table in the Big 12. Will the Longhorns be able to upend the Sooners for a second consecutive year, or will Oklahoma find its revenge and put a likely nail in Strong’s coaching coffin.

Meanwhile, Iowa State looks to lick its wounds against another high-flying Oklahoma State Cowboys squad. In the late game, Texas Tech is eyeing a sweep of the state of Kansas and earn its first road win of the year in the Little Apple against the Kansas State Wildcats.

Below is the complete Big 12 football schedule, along with predictions for each game.

Week 6 Big 12 Football Predictions & Schedule

TCU at Kansas

Date: Saturday, October 8
Time: 12:00 PM
Location: Memorial Stadium
Broadcast: ESPNU

Pick: TCU

Preview and Score Prediction: TCU vs. Kansas

Texas vs. Oklahoma

Date: Saturday, October 8
Time: 12:00 PM
Location: Cotton Bowl
Broadcast: FS1

Pick: Oklahoma

Preview and Score Prediction: Texas vs. Oklahoma

Iowa State at Oklahoma State

Date: Saturday, October 8
Time: 3:30 PM
Location: Boone Pickens Stadium
Broadcast: ESPNU

Pick: Oklahoma State

Preview and Score Prediction: Iowa State vs. Oklahoma

Texas Tech at Kansas State

Date: Saturday, October 8
Time: 7:00 PM
Location:Billy Snyder Family Stadium
Broadcast: ESPNU

Pick: Kansas State

Preview and Score Prediction:Texas Tech vs. Kansas State

MORE: 1-128 College Football Rankings – Week 6